Anorexia, Dexatrim, and Prozac?

Your question brings up a couple of different, complicated issues. First, in regards to your inquiry about the dangers of mixing Dexatrim (an over-the-counter weight loss supplement) and Prozac (generic name: fluoxetine), it may help to know that fluoxetine isn't in the antidepressant class of monoamine oxidase inhibitors (MAOIs). Rather, it's a selective serotonin reuptake inhibitor (SSRI). Nevertheless, due to overlapping negative side effects, it?s best to err on the side of caution and avoid taking both Dexatrim and fluoxetine at the same time. You don't mention whether your friend has been diagnosed with anorexia or whether you've noticed behaviors that are indicative of disordered eating. Either way, in this instance, talking with your friend about your concerns may help provide some clarity for you, as well as give you an opportunity to share your concerns (more on this in a bit). As for your friend?s safety, only their health care provider can accurately assess their physical and emotional well-being, as well as the safety of drug interactions.